- Dysphagia- difficulty swallowing
- Odynophagia - painful swallowing
- Persistent dyspepsia in patients over the age of 45 years
- Heartburn and chronic acid reflux - this can lead to a precancerous lesion called Barrett's esophagus
- Chest and abdominal pain
- Persistent nausea and vomiting
- Severe indigestion
- Hematemesis- vomiting blood.
- Melena stool- blood in the stool (indicating internal GI bleeding)
- Unexplained anemia (low blood count)
- IBD -Inflammatory Bowel Diseases.